Year: 2025

The Switch 2 leaks keep coming

Japanese accessories-maker Genki has released a 3D-printed mockup of what it says is Nintendo’s Switch 2. The mockup was produced using 3D printing technology to show the full size of the Joy-con controllers that are expected to be part of the console. Genki Co-founder Eddie Tsai said the Joy-con will be attached to the console via magnets, instead of a sliding rail.

The ification of Meta is done using X-ification

Facebook-owned social media platform Meta has announced it will end its fact-checking program and cut down its rules barring hate speech in a move allegedly aimed at appeasing President-elect Donald Trump. It has also changed its community guidelines which allow users to make blatantly anti-gay, sexist and racist posts without consequences. Meta said it would be ending its third-party fact-checking program.

The next frontier in genetics is heritable polygenic editing

Researchers have warned that if polygenic genome editing (HPE) is implemented in developing countries, it could result in ” polygenic diseases becoming even more concentrated” in developing countries. HPE can be used to reduce blood pressure, risk factor for common diseases and medical or non-medical applications, they added. It’s possible to modify multiple variants at once, known as polygenic genome editing.

Omi is not just an Artificial Intelligence companion, but is trying to read your mind as well

American startup Omi’s Co-founder Sergey Shevchenko, in an interview with the Verge, said that the startup’s new product Omi helps him understand what he should be working on tomorrow. He further said that Omi’s notifications make no sense, like the one he got after our call. Shevchenko added that he changed the name of the startup to avoid confusion.

There is a functional evaluation and clinical classification of the BRCA 2 variant

A study has revealed that a deep learning model could predict genome-wide variant effects using deep learning-derived scores. The model was developed using ACMG/AMP scoring rules for clinical classification of the BRCA2 SNVs. It predicted variant effects based on gene expression analysis and found that variants in the BRCA1 or BRCA2 are associated with breast, ovarian, pancreatic, and prostate cancer tumours.

There is a model for human cell types

A model for a single-cell accessibility dataset was developed to predict expression in various cell types, including astrocytes. The model was trained on the fetal accessibility and expression atlas. To identify accessible regions specific to each cell type, peak calling results from the original studies of each dataset were used to obtain a union set of peaks.

Despite the rosy predictions, embryo editing against disease is unsafe and has no proven success

Polygenic genome editing in human embryos can reduce the chances of certain diseases, but it raises new concerns of the threat of eugenics, according to a study published in the journal Nature Biotechnology. The researchers found that in some cases, editing a single variant associated with a polygenic disease can have strong effects. edit up to ten genes associated with a disease can reduce its lifetime prevalence.

The partners say that they were blindsided by the Decision to Axe Them

Facebook’s Meta fact-checking platform is terminating its partnership with Poynter Institute and the International Fact-Checking Network. The Poynter Institute and the International Fact-Checking Network are among the fact-checking partners on Meta. Notably, the Poynter Institute also operates PolitiFact, which is an Meta fact-checking partner. Meta said the move was due to it making “too many mistakes”.

The emergence of quantum mechanics a century ago

Lucy Mensing, a founding member of the ‘Interdisciplinary Group on Heligoland’, worked out some of the first applications of his quantum-mechanical theory in the 1970s, Daniela Monaldi, a historian at York University in Toronto, Canada said. Heisenberg had developed a theory of motion in which electrons could no longer be thought of as particles that move along continuous trajectories.

Police say the man who blew up Cybertruck in Las Vegas used a planning tool

Matthew Livelsberger, the US soldier who blew up a Tesla Cybertruck in Las Vegas on New Year’s Day, used generative AI including ChatGPT to help plan the attack, Las Vegas police said. Livelsberger left notes saying that the explosion was a stunt meant to be a “wake up call” for the nation’s troubles, officials said last week.